Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Hydrolysis

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
experimental data of read across substances
Justification for type of information:
Data for the target chemical is summarized based on the structurally similar read across chemicals
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
WoE report is based on three hydrolysis studies as-
2. and 3.
GLP compliance:
not specified
Radiolabelling:
not specified
Analytical monitoring:
not specified
Positive controls:
not specified
Negative controls:
not specified
Transformation products:
not specified
Type:
not specified
Remarks on result:
other: 2. Not expected to undergoes hydrolysis.
Type:
not specified
Remarks on result:
other: 3. lack of hydrolysable fuctional group
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, it is concluded that test chemical was considered to be stable in water.
Executive summary:

Data available for its structurally similar read across chemicals has been reviewed to determine the hydrolysis of the test chemical. The studies are as mentioned below:

In first study it was mentined that Aromatic amines are generally resistant to aqueous environmental hydrolysis therefore,test chemical is not expected to hydrolyze in water.

In another study the test chemical is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions Therefore, test chemical was considered to be stable in water.

On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, it is concluded that test chemical was considered to be hydrolytically stable.

Description of key information

On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, it is concluded that test chemical was considered to be stable in water.

Key value for chemical safety assessment

Additional information

Data available for its structurally similar read across chemicals has been reviewed to determine the hydrolysis of the test chemical. The studies are as mentioned below:

In first study it was mentined that Aromatic amines are generally resistant to aqueous environmental hydrolysis therefore,test chemical is not expected to hydrolyze in water.

In another study the test chemical is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions Therefore, test chemical was considered to be stable in water.

On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, it is concluded that test chemical was considered to be hydrolytically stable.