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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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The critical effect of N, N-dimethylisopropylamine in humans is like for the other tertiary amines, the appearance of visual disturbances (blue haze). 36 out of 47 workers of a foundry (Wolf et al., 1988), that were exposed to a maximal concentration of 3.6 ppm of N, N-dimethylisopropylamine, reported visual disturbances retrospectively. However, a NOEL is not deducible from this study. The structural analogue  N, N-dimethylethylamine (Stälbom et al., 1991; Warren and Selchan, 1988) induced also visual disturbances in similar concentrations.