Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 429-300-3 | CAS number: 155601-30-2 PYRAZOL P5; PYRAZOLE DHE
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: guideline study under GLP conditions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate
- EC Number:
- 429-300-3
- EC Name:
- 1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate
- Cas Number:
- 155601-30-2
- Molecular formula:
- C5H12N4O5S
- IUPAC Name:
- 2-(4,5-diamino-1H-pyrazol-1-yl)ethan-1-ol; sulfuric acid
- Details on test material:
- Batch GST 7-18099
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Water solubility (under test conditions): 660mg/l
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- max Age 24 hours
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 18-20°C
- pH:
- 7.7-7.9 pH
- Dissolved oxygen:
- 8.3-8.6 mg/l
- Salinity:
- hardness 251 mg/l CaCo3 and 2.5 mmol/L Ca/Mg ions proportion 4:1
- Details on test conditions:
- hardness 251 mg/l CaCo3 and 2.5 mmol/L Ca/Mg ions proportion 4:1
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 30.01 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% confindence
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 11.12 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% confidence
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EC50 of Pyrazole DHE at 24 h is 30.01 mg/l and 48h 11.12 mg/l.
- Executive summary:
The study was perfomed according OECD Guidelinee 202.
The animals were treated and observed for 48 hours. No animal in the control group were immobilisized. The EC50 of Pyrazole DHE at 24 h was 30.01 mg/l and at 48h 11.12 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
