Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-783-1 | CAS number: 126-33-0
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The available data from standard studies suggest that sulfolane is not readily biodegradable under either aerobic or anaerobic conditions. Non-standard studies suggest that sulfolane will inherently biodegrade in the presence of a population of sulfolane degrading bacteria under aerobic conditions and these are discussed in more detail in a weight of evidence assessment for degradation of sulfolane appended to IUCLID Section 13 or Annex 3 of the CSR.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, not fulfilling specific criteria
Additional information
The available data from standard studies suggest that sulfolane is not readily biodegradable under either aerobic or anaerobic conditions. An OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) (CITI 1992) reported 10.1 % of the substance degraded within 2 weeks and QSAR predictions with Biowin V4.1 do not predict the substance to be readily biodegradable. Non-standard studies suggest that sulfolane will biodegrade in bioreactors in the presence of a population of sulfolane degrading bacteria under aerobic conditions (Chou and Swatloski 1983; Ying et al. 1994). The oxidation of sulfolane is given in the following equation C4H8O2S + 6.5O2→4CO2+ 3H2O + 2H++ SO42-(Chou and Swatloski 1983). Greene et al. (2000) demonstrated that a mixed population of bacteria has greater capacity for complete mineralisation of sulfolane than some isolated bacterial populations. They identified n-butanol and butyrate as temporary intermediates in sulfolane degradation. There is often a lag period as number of competent degraders capable of cleaving the heteroatomic rings of sulfolane increase but once degradation commences it usually degrades rapidly to CO2, biomass, soluble organic carbon, water and sulphate (Greene et al. 2000).
Sulfolane will not readily biodegrade under anaerobic conditions (Kim et al. 2000).
In summary, sulfolane is not readily biodegradable but is expected to be degraded rapidly by populations of adapted sulfolane degrading bacteria, and if optimal conditions are provided.A weight of evidence assessment for degradation of sulfolane is appended to Section 13.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
