Registration Dossier
Registration Dossier
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EC number: 238-778-0 | CAS number: 14726-36-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- July 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- 2.3 µg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 26 h
- Temp.:
- 20 °C
- pH:
- 7.5
- Remarks on result:
- other: mean value based on the flow rates. See 'Any other information on results incl. tables'.
- Details on results:
- The results are tabulated in 'Any other information on results incl. tables'
- Conclusions:
- The water solubility of the substance was determined to be 2.30 µg/L using the column elution method in accordance with OECD TG 105 and in compliance with GLP.
Reference
Table: Water solubility results
Sample |
Time (hours) |
pH |
Test item concentration (µg/L) |
|
Flow rate of 25 mL/h |
Flow rate of 12.5 mL/h |
|||
1 |
1 |
7.5 |
(1.87)* |
(1.87) |
2 |
2 |
(1.92) |
(1.64) |
|
3 |
3 |
2.57 |
(1.70) |
|
4 |
4 |
2.38 |
2.15 |
|
5 |
5 |
2.96 |
1.87 |
|
6 |
6 |
2.61 |
2.05 |
|
7 |
22 |
2.12 |
1.86 |
|
8 |
23 |
2.37 |
1.68** |
|
9 |
24 |
2.80 |
2.32 |
|
10 |
26 |
2.55 |
2.09 |
|
Mean values for each column |
2.53 |
2.06 |
||
Mean value |
2.30 |
|||
* Unretained value (differ by more than ± 30%)
** Outlier value
Description of key information
The water solubility of the substance was determined to be 2.30 µg/L using the column elution method in accordance with OECD TG 105 and in compliance with GLP.
Key value for chemical safety assessment
- Water solubility:
- 2.3 µg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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