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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

No toxic effects occur within the range of solubility

Key value for chemical safety assessment

Additional information

A non-GLP guideline study according to OECD 202 (1984) was performed to determine the EC50 of the test substance in Daphnia magna.

The respective EC0 at 24h was < 3.2 mg/L and the EC100 was 18 mg/L. All three values are based on nominal concentrations, which were verified by analytical determinations. The compound was initially suspended in alkylphenol polyglycolether and tetrahydrofuran and dispersed in water. The test compound was present as a suspension and a precipitate formed shortly after the start of the test at concentrations between 3.2 and 32 mg/L.

In a non-GLP guideline study according to OECD 202 (1984), the EC50 of a structural analogue was determined to be 740 mg/L inDaphnia magna. Though some deviations from the guideline were employed (e.g. study period of 24 h (as in OECD 202; 1984) instead of 48 h, very high vehicle concentration) the test is considered to be valid. Therefore, no toxic effects occur at the range of solubility.

Both effect concentrations are well above the solubility limit of the test substances (water solubility < 1 mg/L, see chapter 4.8 in IUCLID). Therefore, they represent a worst case assumption where water solubility is achieved by excessive use of solvent. In conclusion, the substance shows no effect in the range of water solubility.