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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From March to June 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study (OECD, EPA, etc)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: CIPAC, MT 181 "Solubility in organic solvents" and OECD Guidelines for Testing Chemicals. Test Guideline No. 105, July 1995 and Official Journal of the European Communities No. L383 Part A, 29.12.92 - Method A.6 "Water solubility".
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Reference substance name:
Monobromacetic acid
IUPAC Name:
Monobromacetic acid
Constituent 2
Chemical structure
Reference substance name:
Bromoacetic acid
EC Number:
201-175-8
EC Name:
Bromoacetic acid
Cas Number:
79-08-3
Molecular formula:
C2H3BrO2
IUPAC Name:
2-bromoacetic acid
Details on test material:
- Name of test material (as cited in study report): Monobromacetic acid (MBAA 100%)
- Substance type: organic acid
- Physical state: solid
- Analytical purity: 99.6%
- Purity test date: 99.6%
- Lot/batch No.: 8-4394760
- Expiration date of the lot/batch: August 2010
- Stability under test conditions: Stable
- Storage condition of test material: The test article was stored at room temperature in the dark.

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
> 1 other: kg/L
Medium:
other: n-hexane
Solubility:
> 10 - < 20 g/L

Applicant's summary and conclusion

Conclusions:
After 24 hours stand by at laboratory's temperature, the solubility of the test item in methanol is higher than 1 kg/L. In n-hexane, the solubility ranged from 10 to 20 g/L.