Registration Dossier
Registration Dossier
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EC number: 206-354-4 | CAS number: 330-54-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
The environmental toxicity profile of Diuron has been well defined. Short term and long term tests with species of 3 trophic levels are available for the substance.
The most sensitive trophic level to Diuron exposure proved aquatic plants as evidenced by EC50values for the growth rate ranging from 18.3 to 30.9 µg/L. Short term effects of the substance towards fish and daphnia were of a similar range. The EC50(48 h) values ranged from 1.4 to 22.6 mg/L in Daphnia magna while the LC50(96h) of fish was calculated to be14.7 mg/L. Thus, the test substance is acutely toxic to aquatic plants and organisms.
The long term effects of the test substance to aquatic organisms are investigated for fish andDaphnia, and were of a similar range. The most sensitive chronic toxicity tests using Daphnia magna revealed a NOEC of 0.56 mg/L and the chronic test with fish a NOEC of 0.41 mg/L.
The 30 minute EC50of the test item for respiratory inhibition of activated sludge was 3080mg/L. Since this is > 1000 mg/L, these findings indicate low toxicity of Diuron to sludge microorganisms and inhibition of the degradation activity of activated sludge is not anticipated.
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