Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-194-1 | CAS number: 79-30-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: No data available
Hydrolysis product: Acutely harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 51.25 mg/L
Additional information
Parent compound isobutyryl chloride and hydrolysis product isobutyric acid:
No data are available for the test substance isobutyryl chloride (CAS 79 -30 -1). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and isobutyric acid (CAS 79 -31 -2). Therefore, the short-term toxicity to aquatic invertebrates is assessed on the basis of data on isobutyric acid.The toxicity of isobutyric acid (CAS 79 -31 -2) was tested on the waterflea Daphnia magna in a 48-h acute immobilization test according to German Industrial Standard Guideline DIN 38412, part 11 at concentrations of 0 (water control), 15.625, 31.3, 62.5, 125, 250, and 500 mg/L. Immobilization and other toxic effects were observed 3, 6, 24, and 48 h after initiation of the test. The 48-h EC50 was determined to be 51.25 mg/L (BASF AG, 1989). Based on the results of the read across substance isobutyric acid the test substance isobutyryl chloride is supposed to be acutely harmful to Daphnia magna.
Hydrolysis producthydrochloric acid (HCl):
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 202 with Daphnia magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; OECD 2002).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
