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Diss Factsheets
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EC number: 246-619-1 | CAS number: 25103-58-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity of tert-dodecanethiol to freshwater fish was assessed in 3 studies using a weight of evidence approach. No mortality or sublethal effect was observed for a 96 hours exposure at values already higher than the limit of solubility.
Key value for chemical safety assessment
Additional information
Two acute fish (Danio rerio and Oncorhynchus mykiss) toxicity tests were performed using OECD TG 203, both using a closed design, one in a limit test with a WAF prepared at 100mg/L and the second at a series of lower concentrations but all greater than the limit of solubility. Analytics were insufficient to consider either of these studies as valid. In the zebrafish study, no effect was observed for mortality or sublethal observations but as the tanks had been opened regularly the study is considered as technically flawed. For the trout study inconsistent effects were found in the mid-concentration range but not at lower or higher concentrations consistent with physical effects. In this study insufficient data were available to assess reliability but the test method does not appear otherwise to have been technically flawed.
A further study on O. latipes was conducted in open conditions and the fish were exposed to the substance in an emuslifier was therefore not used in a WoE approach.
Four other studies were also located on fish and are mentioned in the review paper by Thomas & Comber (2013) but are not included in the IUCLID as too little information beyond the effect concentration is available. In all cases no effects were found at or close to the solubility limit of the substance.
The conclusion is no effect on fish at the solubility limit using a weight of evidence approach.
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