Registration Dossier
Registration Dossier
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EC number: 932-185-7 | CAS number: 1187742-72-8
Endpoint summary
Administrative data
Description of key information
Additional information
The assessment is based on the data currently available. New studies, based on the category review and the final decisions issued for some of the category substances, which are also relevant for this assessment, are currently being conducted. The hazard assessment with respect to aquatic toxicity will be updated once all ongoing studies have been finalised.
The alkyl ether sulfates grouped within the AES category show similar structural, physico-chemical, environmental and toxicological properties. The approach of grouping different AES for the evaluation of their effects on human health and the environment was also made by the Danish EPA [1] and HERA [2], supporting the read across approach between structurally related AES.
The aquatic toxicity of the alkyl ether sulfates has been evaluated in studies on fish, invertebrates and algae as well as microorganisms. In most of the given studies AES were tested as sodium salts. As the cation counterpart of the AES anions is not expected to influence the ecotoxicological profile of the substance, read-across is possible between all comparable mixtures independent from the cation (e.g. sodium, magnesium, ammonium, MIPA; for details see category justification).
Concerning the AES (C12-14, 1-2.5EO), short-term studies on freshwater species of three trophic levels (fish, invertebrates and algae) are available for the MIPA salt (CAS 1187742 -72 -8). Chronic endpoints were covered with studies conducted with mixtures comparable to the AES (C12-14, 1-2.5EO) as well as data available for the pure homologues.
The acute and chronic toxicity data of alkyl ether sulfates indicate that fish and invertebrates are more sensitive to AES than algae. However, there is no significant difference in the sensitivity of both organism groups. The LC/EC50 values are reported to be 7.7 mg/L (nominal) for fish and daphnia. For the less sensitive algae the EC50 was 14 mg a.i/L (nominal). For fish one long-term study is available for the AES (C12-14, 2EO) Na mixture (CAS 68891-38-3) resulting in a NOEC of 0.14 mg/L (measured). For daphnids (Daphnia magna) one chronic study is available for the AES (C12-14, 2EO) Na mixture (CAS 68891-38-3) resulting in a NOEC-value of 0.27 mg/L (measured). Chronic tests conducted with Ceriodaphnia dubia using the pure AES homologues (C12, EO1; C14, EO1) and (C12, EO2, C14, EO2) resulted in NOEC (reproduction)-values ranging from 0.31 mg/L to 6.25 mg/L (measured).
The available algae NOEC for the AES (C12 -14, 1 -2.5EO) MIPA (CAS 1187742 -72 -8) salt mixture was 2 mg/L (nominal).
From the results of the tests listed above, a chronic risk of AES (C12 -14, 1 -2.5EO) MIPA on aquatic organisms cannot be excluded.
[1] Danish EPA - Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products (2001). Environmental Project No. 615, pp. 24-28
[2] HERA - Human & Environmental Risk Assessment on ingredients of European household cleaning products (2004). Alcohol Ethoxysulphates (AES).
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