Registration Dossier
Registration Dossier
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EC number: 200-471-4 | CAS number: 60-34-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1.1 mg/L
Additional information
MMH had a nominal 96h-LC50 of 2.58 mg/L in Lebistes reticulatus (a.k.a. Poecilia reticulata: guppy) in a static test. Without analytical follow-up, due to volatility of the undiluted item, this value is likely an overestimate of the actual LC50.
MMH, tested in another static assay in two fish species over 96h, with analytical follow-up, was characterized by LC50:
- between 1.1 and 2.1 mg/L based on measured concentrations, for golden shiner;
- of 3.54 mg/L based on nominal values (overestimate), for channel catfish.
Both studies were Klimisch 4 due to several deviations or missing data, however data in three different fish species, in two independent assays, show a very consistent result: a steep dose-lethality curve with a 96h-LC50 between 1.1 (measured geometrical mean value) and 3.5 (nominal) mg/L. This knowledge is considered largely sufficient for classification and risk assessment in view of the much lower EC50 values obtained in more recent tests in algae and daphnids, showing that fish is by far not the most sensitive trophic level.
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