Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-022-9 | CAS number: 288-88-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50-72h of 45 mg/L for aquatic algae was determined. Therefore, 1,2,4 triazole is considered as harmful to algae.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 45 mg/L
- EC10 or NOEC for freshwater algae:
- 3.5 mg/L
Additional information
The acute toxicity of 1,2,4 Triazole to Pseudokirchnerella subcapitata has been investigated in an OECD 201 test according to GLP requirements (Thiebaud & Bouraly, 1998). In the test conditions, the ErC50 -72h is 45 mg/L and the NOEC is 3.49 mg/L. The test concentrations were maintained within 80% during the test. Therefore, 1,2,4 Triazole is considered as harmful to algae.
Another test similar to OECD guideline 201 has been performed and can be used as a supportive study (De Morsier, 1982). The cell concentration was determined at 120 hours instead of at least at 24, 48 and 72 hours after the start of the test. Therefore only an EC50-value after 5 days is given. in addition, concentrations were not maintained within 80% during the test. The EC50 -5d was determined to be 6.3 mg/L (nominal concentrations).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
