Registration Dossier
Registration Dossier
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EC number: 203-058-7 | CAS number: 102-82-9
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1973
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Unsuitable test system
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
Materials and methods
- Type of study / information:
- Nitrosation of amines
- Principles of method if other than guideline:
- no guideline required
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Tributylamine
- EC Number:
- 203-058-7
- EC Name:
- Tributylamine
- Cas Number:
- 102-82-9
- Molecular formula:
- C12H27N
- IUPAC Name:
- tributylamine
- Details on test material:
- - Name of test material (as cited in study report): tri-n-butylamine, not further specified
Constituent 1
Results and discussion
Any other information on results incl. tables
Di-n-butylnitrosoamine was formed from 0.5 M,0.1 M, and 0.02 M tri-n-butylamine in the presence of excess nitrite (4-molar excess) at a yield of 14 %, 1 % and 0.4 % after 4h at pH 3.7 - 4.0 and 37 °C, respectively.
Applicant's summary and conclusion
- Executive summary:
Di-n-butylnitrosoamine was formed from 0.5 M,0.1 M, and 0.02 M tri-n-butylamine in the presence of excess nitrite (4-molar excess) at a yield of 14 %, 1 % and 0.4 % after 4h at pH 3.7 - 4.0 and 37 °C, respectively (Lijinski et al., 1973).
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