Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Evidence from two studies in guinea pigs indicates that diethyltoluenediamine does not possess skin sensitization potential (Gabriel 1977; Nelson et al. 1977).

Migrated from Short description of key information:
Two sensitization studies with guinea pigs demonstrated that the test material is not a sensitizing agent (Gabriel 1977; Nelson et al. 1977).

Justification for classification or non-classification

The negative findings reported by Gabriel (1977) and Nelson et al. (1977) support that the test substance is not a skin sensitizing agent. Therefore, the GHS criteria for classification are not applicable to this substance. See: Regulation (EC) No 1272/2008; See Official Journal of the European Union, (2008) Vol. L353, pp. 1-1355, at p. 97.