2-(2H-benzotriazol-2-yl)-p-cresol

Additional toxicological data

Administrative data

Endpoint:

additional toxicological information

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

3 (not reliable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1964

Report date:

1964

Materials and methods

Type of study / information:

Phototoxicity

Test guideline

Qualifier:

no guideline available

Principles of method if other than guideline:

Each agent was applied to the backs of ten (10) men under occlusion for twenty-four (24) hours. A control site was treated with petrolatum. Then, one minimal erythema dose was given to the treated and control sites using the erythema producing radiation produced by the Westinghouse FS-20 lamp. Photo-toxicity is indicated by a marked flare at the sites treated by the test agents.

GLP compliance:

no

Remarks:

Study pre-dates GLP

Test material

Test material information

Constituent 1

Reference substance name:

2-(2H-benzotriazol-2-yl)-p-cresol

EC Number:

219-470-5

EC Name:

2-(2H-benzotriazol-2-yl)-p-cresol

Cas Number:

2440-22-4

Molecular formula:

C13H11N3O

IUPAC Name:

2-(2H-1,2,3-benzotriazol-2-yl)-4-methylphenol

Test material form:

solid

Specific details on test material used for the study:

- Name of test material (as cited in study report): Tinuvin P

Results and discussion

Any other information on results incl. tables

A table of results is provided in the study report; however, the results were not fully described. It was concluded in the study report that CAS 2440 -22 -4 was not phototoxic.