Registration Dossier
Registration Dossier
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EC number: 203-612-8 | CAS number: 108-74-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is found to be readily biodegradable and the applied test concentrations are in the range of concentrations that can be expected in the influent of a sewage treatment plant
Reference
Description of key information
The NOEC used to define the toxicity to microorganisms endpoint was obtained from the OECD 306 biodegradability study (Drake, 2007). The addition rate of 3.04 mg/L, with 28-days exposure, showed no inhibition to microorganisms which degraded the substance by 73 % after 14-days.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 3.04 mg/L
Additional information
In a biodegradation in water simulation test, conducted in accordance with OECD 306, an addition rate of 3.04 mg/L showed no inhibition to microorganisms which degraded the substance by 73 % after 14 -days. The exposure time was 28 -days, and in accordance with ECHA Guidance on Information Requirements and Chemical Safety Assessment, Chapter R10, this value can be used to derive the PNECstp.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
