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EC number: 203-852-3 | CAS number: 111-27-3
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
The water solubility of a commercial hexan-1-ol product is 1300 mg/L at 23°C and pH 5.5. A value of 5900 mg/L at 25°C is available for the pure alcohol, from a reliable and definitive reference source for solubility data (Yalkowsky and Valvani, 1980).
Key value for chemical safety assessment
- Water solubility:
- 1 300 mg/L
- at the temperature of:
- 23 °C
Additional information
The solubility of 1300 mg/L at 23°C and pH 5.5 was determined with the use of a flask method in accordance with ASTM E 1148. The result is considered to be reliable.
It is supported by a value of 5900 mg/L at 25°C, taken from a reliable and definitive reference source for solubility data (Yalkowsky and Valvani, 1980). Other reference sources gave a consistent result.
The value taken from literature for pure alcohol is used in exposure modelling.
Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:
As chain length increases, water solubility decreases, because the free energy required for a molecule to dissolve becomes less favourable for larger molecules.
Reference:
Yalkowsky and Valvani, 1980: J.Pharm Sci 69 912 (1980), taken from Satyanarayana, D.; Charyulu, R. Narayana; and Nagavi, B. G., Asian Journal of Chemistry (1997), 9(3), 418-426
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