Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
96-96-8
Author:
Danish EPA model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Multicase model is used to estimate IGC50 (46h) of tetrahymena pyriformis.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-nitro-p-anisidine
EC Number:
202-547-2
EC Name:
2-nitro-p-anisidine
Cas Number:
96-96-8
Molecular formula:
C7H8N2O3
IUPAC Name:
4-methoxy-2-nitroaniline

Test organisms

Test organisms (species):
Tetrahymena pyriformis

Study design

Test type:
not specified
Water media type:
not specified
Limit test:
yes
Total exposure duration:
46 h

Results and discussion

Effect concentrations
Duration:
46 h
Dose descriptor:
other: IG50
Effect conc.:
49.056 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes