Registration Dossier
Registration Dossier
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EC number: 222-389-8 | CAS number: 3457-61-2
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
A long-term toxicity testing on aquatic invertebrates has been performed (Chastenet, 2018) following the final decision of ECHA on testing proposals (ECHA decision number TPE-D-2114319122-65-01/F). Indeed, based on acute aquatic toxicity data, neither fish nor daphnia are shown to be substantially more sensitive. Therefore, according to the integrated testing strategy, the long-term daphnia study has been conducted first. Based on the results of this test and the application of the relevant assessment factor, no risks are observed (PEC/PNEC<1) for the aquatic compartment. Therefore, in accordance with the ECHA guidance (Chapter R7b, version 2.0 Figure R.7.8-4) and the final decision of ECHA, no long-term fish testing need to be conducted.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
