Registration Dossier
Registration Dossier
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EC number: 286-075-2 | CAS number: 85186-89-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the water solubility limit (< 1 mg/L) for aquatic algae (OECD 202/ISO 14669).
Key value for chemical safety assessment
Additional information
Four studies, investigating the toxicity to freshwater algae, and one study, investigating the toxicity to saltwater algae, of Fatty acids, C8-10 (even), C14-18 (even) and C16-18 (even)-unsatd., triesters with trimethylolpropane (former CAS 85186-89-6), are available. In the static GLP-freshwater key study (Wierich and Özkabakcioglu, 1999) with Desmodesmus subspicatus according to EU Method C.3 shows an EL50 (72 h) > 100 mg/L (WAF loading rate) based on the growth rate. Both other static GLP-freshwater studies (both: Craig, 2005) with Pseudokirchneriella subcapitata according to OECD 201 showed significant inhibition of the growth rate (58% and 67%) at the highest test concentration (1000 mg/L WAF loading rate). Because of the serial dilution from the highest concentration (1000 mg/L) in both studies, only the 1000 mg/L test concentration was valid and could be used for evaluation of toxicity of the test substance. Therefore, the ErL58 and ErL67 were determined as 1000 mg/L. In the static GLP-saltwater study (Hudson, 2005) with Skeletonema costatum according to ISO 10253 the EL50 was calculated as 9865.86 mg/L and the NOELR as 3200 mg/L. Overall, all data show adverse effects of Fatty acids, C8-10 (even), C14-18 (even) and C16-18 (even)-unsatd., triesters with trimethylolpropane (former CAS 85186-89-6) only far in excess of natural occurring concentrations (water solubility < 1 mg/L). Therefore, the substance is not harmful to freshwater and marine algae.
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