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Partition coefficient

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Description of key information

Measured log Pow= >6.5 at 23°C at pH 6.4

Estimated based on solubility ratio:

logPow= >6.8 <7.4 at 23°C

Key value for chemical safety assessment

Additional information

The partition coefficient was measured by HPLC and estimated from the single solubilites in n-octanol and in water.

Additionally, the partition coefficient have been calculated using different programs as recommended in Guideline.

- The results by calculation using ACD/Labs were given as follows:

logD= 7.4 at pH 4-7 at 25°C

logD= 7.0 at pH 8 at 25°C

logD= 6.2 at pH 9 at 25°C

- The result by calculation using KOWWIN module was given a log Pow value of 6.2 at 25°C