Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 700-258-0 | CAS number: 125971-95-1
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- (Q)SAR
- Adequacy of study:
- other information
- Study period:
- not aplicable
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: (Q)SAR Toxcheck is in silico predition tool
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Materials and methods
- Type of study / information:
- (Q)SAR Toxcheck in silico predition tool
- Principles of method if other than guideline:
- none
Test material
- Reference substance name:
- tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
- EC Number:
- 700-258-0
- Cas Number:
- 125971-95-1
- Molecular formula:
- C40H47FN2O5
- IUPAC Name:
- tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
- Details on test material:
- none
Constituent 1
Results and discussion
Any other information on results incl. tables
none
Applicant's summary and conclusion
- Conclusions:
- none
- Executive summary:
According to (Q)SAR evaluation the substance:
has no toxicity alerts (no mutagenicity alert)
has low cardiac toxicity risk
can cause drug-drug interactions
is unlikely to cause photoirritations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
