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Diss Factsheets

Ecotoxicological information

Toxicity to other aquatic organisms

Currently viewing:

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1995
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: no glp, no methode, citated by RIVM
Justification for data waiving:
other:

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
primary sourece:
Sauvant MP, Pepin D, Groliere CA, Bohatier J. 1995a. Effects of organic and inorganic
substances on the cell proliferation of L-929 fibroblasts and Tetrahymena pyriformis GL
protozoa used for toxicological bioassays. Bull Environ Contam Toxicol 55: 171-178.
Sauvant MP, Pepin D, Bohatier J, Groliere CA. 1995b. Microplate technique for screening
and assessing cytotoxicity of xenobiotics with Tetrahymena pyriformis. Ecotoxicol
Environ Saf 32: 159-165.
Sauvant MP, Pepin D, Bohatier J, Groliere CA, Guillot J. 1997. Toxicity assessment of 16
inorganic environmental pollutants by six bioassays. Ecotoxicol Environ Saf 37: 131-140.
Savant KB, Nilkanth GV. 1991. On comparative studies of acute toxicity of hexavalent
chromium and selenium to Scylla serrata (Forskal). Pollut Res 10: 239-243.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
stannous dichloride
IUPAC Name:
stannous dichloride

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Tetrahymena pyriformis

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
9 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
9 h
Dose descriptor:
IC50
Effect conc.:
90 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
dissolved
Remarks:
Sn
Basis for effect:
other: growth
Duration:
9 h
Dose descriptor:
IC50
Effect conc.:
54 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
dissolved
Remarks:
Sn
Basis for effect:
other: groth

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
IC50(9h)=54 mg/L