(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: screening tests

Adequacy of study:

disregarded due to major methodological deficiencies

Data waiving:

other justification

Justification for data waiving:

other:

Data source

Reference

Reference Type:

other: Body responsible for the test

Title:

Unnamed

Materials and methods

Study design

Reference substance

Reference substance:

other: Sodium benzoate

Results and discussion

% Degradation

Value:

< 1

Sampling time:

28 d

Details on results:

Points of degradation plot (test substance):
0 % degradation after 2 d
0 % degradation after 4 d
0 % degradation after 6 d
0 % degradation after 8 d
0 % degradation after 10 d
0 % degradation after 15 d
0 % degradation after 20 d
0 % degradation after 23 d
.5 % degradation after 28 d

BOD5 / COD results

Results with reference substance:

Points of degradation plot (reference substance):
21 % degradation after 2 d
38 % degradation after 4 d
49 % degradation after 6 d
55 % degradation after 8 d
57.5 % degradation after 10 d
64 % degradation after 15 d
69 % degradation after 20 d
72.5 % degradation after 23 d
80 % degradation after 28 d

Applicant's summary and conclusion

Interpretation of results:

other: not readily biodegradable