Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-509-8 | CAS number: 107-66-4
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: special investigation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
Materials and methods
- Type of study / information:
- Metabolism and kinetics of the herbicide aminophon were evaluated.
- Principles of method if other than guideline:
- The herbicide 32P-Aminophon was applied oral, ip and sc to rats. Metabolism and kinetics of aminophon was evaluated.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Aminophon (O,O-di-n-butyl-1-n-butyl-amino-cyclohexyl-phosphonate)
- IUPAC Name:
- Aminophon (O,O-di-n-butyl-1-n-butyl-amino-cyclohexyl-phosphonate)
- Details on test material:
- no data
Constituent 1
Results and discussion
Any other information on results incl. tables
Metabolism:
After i.p.administration of the pesticide aminophon
(O,O-di-n-butyl-1-n-butyl-amino-cyclohexyl-phosphonate) to rats, dibutyl
hydrogen phosphate was detectable in the urine among
other metabolites; orally administered aminophon also yielded dibutyl
hydrogen phosphate, but to a lesser amount, in the urine.
Applicant's summary and conclusion
- Conclusions:
- After i.p. administration of the pesticide aminophon (O,O-di-n-butyl-1-n-butyl-amino-cyclohexyl-phosphonate) to rats, dibutyl hydrogen phosphate was detectable in the urine among other metabolites; orally administered aminophon also yielded dibutyl hydrogen phosphate, but to a lesser amount, in the urine.
- Executive summary:
The herbicide 32P-Aminophon was applied oral, ip and sc to rats. Metabolism and kinetics of aminophon was evaluated.
Metabolism:
After i.p. administration of the pesticide aminophon (O,O-di-n-butyl-1-n-butyl-amino-cyclohexyl-phosphonate) to rats, dibutyl hydrogen phosphate was detectable in the urine among other metabolites; orally administered aminophon also yielded dibutyl hydrogen phosphate, but to a lesser amount, in the urine.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
