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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1988-02
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
activated sludge of a predominantly domestic sewage
Details on inoculum:
laboratory scale sewage treatment plant treating synthetic sewage (OECD 209)
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h
Test temperature:
20.4
pH:
8.4
Dissolved oxygen:
start: 3.2 mg
end: 2.3 mg
Nominal and measured concentrations:
nominal: 100, 1000 and 10000 mg/L

Details on test conditions:
- test concentration of activated sludge: 6 g/L (dry matter)
Reference substance (positive control):
yes
Remarks:
3,5-Dichlorophenole
Key result
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 10 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate
Validity criteria fulfilled:
yes
Conclusions:
According to the OECD Guideline 209 dibutyl hydrogen phosphate was exposed to activated sludge of a predominantly domestic sewage. An 3h-EC50 of > 10000 mg/L was obtained.
Executive summary:

A study was performed to assess the toxicity of dibutyl hydrogen phosphate to microorganisms. The study was conducted according to the OECD Guideline 209. The activated sludge was exposed to dibutyl hydrogen phosphate at different concentrations. The respiration rate of each mixture was determined after aeration periods of 3 hours. Dibutyl hydrogen phosphate showed no respiration inhibition of activated sludge at a concentration of 10000 mg/L. The EC50 is higher than 10000 mg/L.

The effect value related to nominal concentration, since no analytical monitoring was performed.

Description of key information

Dibutyl hydrogen phosphate was exposed to activated sludge of a predominantly domestic sewage. An 3h-EC50 of > 10000 mg/L was obtained.

Key value for chemical safety assessment

EC50 for microorganisms:
10 000 mg/L

Additional information

A study was performed to assess the toxicity of dibutyl hydrogen phosphate to microorganisms. The study was conducted according to the OECD Guideline 209. The activated sludge was exposed to dibutyl hydrogen phosphate at different concentrations. The respiration rate of each mixture was determined after aeration periods of 3 hours. Dibutyl hydrogen phosphate showed no respiration inhibition of activated sludge at a concentration of 10000 mg/L. The EC50 is higher than 10000 mg/L.

The effect value related to nominal concentration, since no analytical monitoring was performed.