Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable data, report with limited documentation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973
Report date:
1973

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
An acute dermal toxicity study on rabbits was performed
GLP compliance:
not specified
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
7-hydroxycitronellal
EC Number:
203-518-7
EC Name:
7-hydroxycitronellal
Cas Number:
107-75-5
Molecular formula:
C10H20O2
IUPAC Name:
7-hydroxy-3,7-dimethyloctanal
Test material form:
not specified
Details on test material:
- Name of test material (as cited in study report): Hydroxycitronellal
- Sample marking: SA-11-2490
no further data given

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
2000 mg/kg
No. of animals per sex per dose:
2 animals used
Control animals:
other: not applicable
Details on study design:
- Duration of observation period following administration: 14 days
- Frequency of observations: daily

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
no mortality observed
Clinical signs:
other: Symptomatology: none

Applicant's summary and conclusion