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EC number: 481-670-5 | CAS number: 848301-66-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
- key information: (96h) LL50 for freshwater fish (Brachydanio rerio ): >1000 mg/l [OECD 203; test mat. 'Kerosine (Fischer-Tropsch), full range, C8-16 branched and linear' (WAFs) (nominal) based on: mortality];
- supporting information: (96h) LL50 for freshwater fish (Oncorhynchus mykiss): >100 mg/l [OECD 203; test mat. 'Kerosine (Fischer-Tropsch), full range, C8-16 branched and linear' (WAFs) (nominal) based on: mortality].
Key value for chemical safety assessment
Additional information
The acute toxicity of a sample of GTL Kerosine has been determined in a test with the fish Brachydanio rerio(Zebrafish). The test was conducted in accordance with OECD Test Guideline 203 and GLP (Xiang, 2008).
Water accommodated fractions (WAFs) were prepared at a nominal concentration of 1000 mg/l and the test was performed with semi-static test medium renewal. There is no indication in the study report that any measures were taken to prevent or minimise volatile losses from the test system. However, Total Organic Carbon (TOC) analysis showed no measureable difference between fresh and expired test solutions. There were no abnormalities or deaths during the 96 hour exposure period.
The test results, expressed as the LL50value, showed that the sample was not acutely toxic to fish at a loading rate of 1000 mg/l. This has been chosen as the key study because it is the most reliable study with a higher limit value.
A study from Harlan (Goodband, 2011a) has also reported no toxicity at the limit value of 100 mg/l (tested as WAFs) with the freshwater fish Oncorhynchus mykiss. The study has been assigned reliability 2. A validation of mixing period pre-study had been conducted. A 24 hour mixing period and a 96 hour mixing period result in 1.68 mg C/l and 5.44 mg C/l, respectively, and corrected for control carbon. The 24 hour mixing period was chosen for the definitive test. The TOC analysis for the definitive test did not allow for the background concentration of TOC to be distinguished from the loaded test substance TOC concentration in solution.
The following information is taken into account for short-term toxicity to freshwater fish: (96-h) LL50>1000 mg/l B. rerio (reliability 1).
Value used for CSA: LL50for freshwater fish:>1000 mg/l.
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