Registration Dossier
Registration Dossier
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EC number: 271-360-6 | CAS number: 68551-08-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysis of an organic molecule occurs when a molecule (R-X) reacts with water (H2O) to form a new carbon-oxygen bond after the carbon-X bond is cleaved. Mechanistically, this reaction is referred to as a nucleophilic substitution reaction, where X is the leaving group being replaced by the incoming nucleophilic oxygen from the water molecule. Chemicals that are susceptible to hydrolysis contain functional groups that can be displaced by a nucleophilic substitution reaction. Substances that have the potential to hydrolyze include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters. The lack of a leaving group renders a compound resistant to hydrolysis. Alkyl alcohols are resistant to hydrolysis because they lack a functional group that is hydrolytically reactive. Therefore, this fate process will not contribute to a measurable degradative loss of this substance from the environment.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
