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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
yes
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
2.9
Temp.:
25 °C
pH:
11.9

Measurment conditions 1: 2.92 & 2.91 (mean 2.92)

Measurment conditions 2: 2.91 & 2.90 (mean 2.90)

Measurment conditions 3: 2.90 & 2.89 (mean 2.89)

Conclusions:
The log Pow values measured through the six experiments did fall within a range of ± 0.3 units
Executive summary:

The partition coefficient 1,3 Di-o-Tolylguanidine was evaluated in a study performed in accordance with OECD testing guideline 107 and GLP requirements. The partition coefficient was of 2.9.


Validity criteria were fulfilled.

Description of key information

Log Kow 1,3 Di-o-Tolylguanidine = 2.9
Study performed in accordance with:
- OECD testing guideline 107 and 
- GLP requirements

Key value for chemical safety assessment

Log Kow (Log Pow):
2.9
at the temperature of:
25 °C

Additional information

The partition coefficient 1,3 Di-o-Tolylguanidine was evaluated in a study performed in accordance with OECD testing guideline 107 and GLP requirements.


The partition coefficient is 2.9.