Registration Dossier
Registration Dossier
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EC number: 700-280-0 | CAS number: 1869-24-5
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-(trifluoromethyl)benzene-1-sulfonamide
- EC Number:
- 700-280-0
- Cas Number:
- 1869-24-5
- Molecular formula:
- C7H6F3NO2S
- IUPAC Name:
- 2-(trifluoromethyl)benzene-1-sulfonamide
- Reference substance name:
- 2-(Trifluoromethyl)benzenesulfonamide
- IUPAC Name:
- 2-(Trifluoromethyl)benzenesulfonamide
Constituent 1
Constituent 2
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 4 600 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 1 % significance level
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 640 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 1 % significance level
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100.5 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Conclusions:
- Based on the nominal concentrations the mean lethal concentration LC50(96 h) is >4600 mg/L. The no observed effect concentration NOEC(96 h) is 100 mg/L.
Based on the analytically detected concentrations the mean lethal concentration LC50(96 h) is > 640 mg/L. The no observed effect concentration NOEC(96 h) is 100.5 mg/L.
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