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Environmental fate & pathways

Adsorption / desorption

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Description of key information

Due to the measured and calculated Koc values the substance is not supposed to strongly bind to solid soil phase. Hence, adsorption is not an important fate path in the environment.

Key value for chemical safety assessment

Koc at 20 °C:

Additional information

A GLP test according to OECD guideline 106 using 4 different soils was performed applying radioactive material for detection (BASF, 295/162-D2149, 2003). Koc were estimated to be in the range of 4 -19 for all soils. This result is supported by a calculation using EpiSuite v4.11 (BASF, 2017). Using the molecular connectivety index (MCI) method, the Koc was calculated to be 4.776 L/kg (log Koc=0.6791). With the Kow method a Koc of 1.697 L/kg (log Koc= 0.2297) was calculated.

Based on measured and calculated Koc values, adsorption to the soil phase is not expected for the test substance (log Koc < 3).

In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of 2-Imidazolidone (Q)SAR results were used for adsorption/desorption. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on adsorption/desorption are not provided.