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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Key value for chemical safety assessment

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The three estimations with BCFBAF v3.01 calculate an average level of BCF values of Fatty acids, C16 -18 and C18 -unsatd., Me esters, epoxidized, reaction products with ethylene glycol; Mono-, Di, and Tri-Adduct:

- Mono-Adduct of Fatty acids, C16 -18 and C18 -unsatd., Me esters, epoxidized, reaction products with ethylene glycol:

EPISuite v4.1/BCFBAFv3.01: A BCF value of 60.32 (log BCF = 1.780) was estimated on the basis of the log Kow of 5.29. Using the Arnot-Gobas method including biotransformation rates the BCF for the upper trophic level was estimated at 23.9 (log BCF = 1.378) (BASF, 2013).

- Di-Adduct of Fatty acids, C16 -18 and C18 -unsatd., Me esters, epoxidized, reaction products with ethylene glycol:

EPISuite v4.1/BCFBAFv3.01: A BCF value of 15.46 (log BCF = 1.189) was estimated on the basis of the log Kow of 11.77. Using the Arnot-Gobas method including biotransformation rates the BCF for the upper trophic level was estimated at 0.8945 (log BCF = -0.048) (BASF, 2013).

- Tri-Adduct of Fatty acids, C16 -18 and C18 -unsatd., Me esters, epoxidized, reaction products with ethylene glycol:

EPISuite v4.1/BCFBAFv3.01: A BCF value of 3.162 (log BCF = 0.500) was estimated on the basis of the log Kow of 18.26. Using the Arnot-Gobas method including biotransformation rates the BCF for the upper trophic level was estimated at 0.893 (log BCF = -0.049) (BASF, 2013).

CONCLUSIONS
BCF values are in the range of 0.893 to 23.9 (Arnot-Gobas-method). Considering mitigating factors like biotransformation, water solubility and molecular size, there is low potential for bioaccumulation. In addition, due to the low water solubility exposure of aquatic organisms to significant amounts is unlikely. Therefore, unacceptable risks due to possible bioaccumulation are not expected. Furthermore, due to a molecular mass greater than 700, the test substance is not readily taken up by fish, because of possible steric hindrance at passage of gill membranes or cell membranes of respiratory organs (Technical Guidance Document on Risk Assessment (TGD) Part 2 (2003), Institute for Health and Consumer Protection, European Chemicals Bureau).In addition, based on current knowledge, a calculated log Kow of 10 or above is taken as an indicator of reduced bioconcentration. (Chapter R.7C-Endpoint Specific Guidance; R7.10.3.4)