Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-281-4 | CAS number: 98362-33-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In the acute immobilization test to Daphnia magna (STRAUS), the effects of the test item 2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid were determined according to OECD 202 (2004).
The study was conducted under static conditions over a period of 48 h with 6 water accommodated fractions (WAF) of the test item. The nominal loadings in the range of 3.125 to 100 mg/L were prepared with dilution water in a geometric series with a dilution factor of 2. Twenty daphnids were exposed to each loading level and the control.
The water accommodated fractions with nominal loadings of the test item of 3.125 to 100 mg/L and the control were analytically verified by analysis of total organic carbon (TOC, according to DIN EN 1484) at the start of the exposure (fresh media, 0 h) and at the end of the exposure (old media, 48 h).
The measured concentrations of total organic carbon in the fresh media (0 h) were in the range of 2.85 to 18.3 mg Carbon/L in the loading levels 3.125 to 100 mg/L. In the old media (48 h), the measured concentrations of total organic carbon were in the range of 3.49 to 16.9 mg Carbon/L in the loading levels 3.125 to 100 mg/L.
All effect values given are based on the nominal loadings of the test item. Water quality parameters (pH-value and dissolved oxygen concentration), measured in the fresh (0 h) and old media (48 h), were within acceptable limits. The validity criteria of the test guideline were fulfilled.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 26.3 mg/L
Additional information
Based on the nominal loadings of the test item 2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid, the 48-h EL50 for Daphnia magna was calculated to be 26.3 mg/L (95 % confidence limits: 23.9 – 30.3 mg/L). The NOEL after 48 h was 12.5 mg/L. The LOEL after 48 h was 25.0 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
