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EC number: 203-224-9 | CAS number: 104-66-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
KS-235 exhibited no respiration inhibition and no dose response was observed. The definitive test was not required and was therefore not
performed. KS-235 also demonstrated no abiotic response.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
Additional information
- KS-235: Assessment of Ready Biodegradability; CO2 Evolution Test
Table 3: Oxygen Consumption Rates and Percentage Inhibition from Preliminary Investigational Work Using the Activated Sludge Respiration Inhibition Test (OECD 209) Method
Nominal Concentration |
O2 Consumption Rates (mg O2/l/min) |
% Inhibition |
|
Control |
R1 |
0.48 |
- |
R2 |
0.39 |
- |
|
KS-235 |
5 mg C/l |
0.42 |
3 |
10 mg C/l |
0.40 |
8 |
|
20 mg C/l |
0.41 |
6 |
|
3,5 dichlorophenol |
3.2 mg/l |
0.44 |
[1] |
32 mg/l |
0.06 |
86 |
|
[increase in respiration rates as compared to the controls]
R1 - R2 = Replicates 1 and 2
- The test material did not inhibit the respiration of sewage sludge micro-organisms at the concentration employed in the test
- An evaluation of the effect of KS-235 on the respiration rate of activated sludge - Preliminary test
Discussion: The study was conducted according to the test guideline. KS-235 exhibited no respiration inhibition and no dose response was observed. The definitive test was not required and was, therefore, not performed. KS-235 also demonstrated no abiotic response. The 3-hour EC50 of KS-235 to activated sludge respiration inhibition was determined to be >1000mg/l during the preliminary study.
3 hour exposure period |
ECxvalues (mg/l) |
||
EC20 |
EC50 |
EC80 |
|
KS-235 |
>1000 |
>1000 |
>1000 |
3,5-DCP (Reference) |
1.20 (1.16 - 1.24) |
6.98 (6.658 - 7.306) |
>18 |
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