Registration Dossier
Registration Dossier
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EC number: 609-336-8 | CAS number: 371756-75-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The substances in the stilbene fluorescent whitening agents category are with high probability acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
Several studies are available in order to determine the acute toxicity of several substances belonging to the stilbene fluorescent whitening agents category to fish. Six of those studies demonstrate that the substances belonging to the category are with a high probability acutely not harmful to fish. In one study, the LC50 values determined were significantly lower than in the studies mentioned before (CIBA-GEIGY G09304, 1991). Due to the number of studies that demonstrated that the category members are not harmful to fish, this study was considered as an outlier and not regarded for classification. Therefore, reading across, also the substance with CAS 371756 -75 -1 is considered with high probability acutely not harmful to fish.
CAS 16090-02-1: Three weight of evidence studies point to the fact that the LC50 value in fish exceeds 100 mg/L. This result is substantiated by two other studies on substances in the stilbene fluorescent whitening agents category which the test substance is a member of. In another study, the LC50 values determined were significantly lower than the studies mentioned before (CIBA-GEIGY G09304, 1991).
CAS 41098-56-0: In a short-term toxicity study of the test substance on rainbow trout, no toxic effects occured at the test concentration of nominally 100 mg/L (CIBA-GEIGY 2008). Therefore, the test substance is considered not to be harmful to fish.
CAS 16470-24-9: The LC50 value of the test substance on zebra fish according to OECD 203 was found to be greater than 1000 mg/L (CIBA-GEIGY 1992)
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