Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-209-5 | CAS number: 3031-66-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1958
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: early study report; only marginal details given
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 958
- Report date:
- 1958
Materials and methods
- Principles of method if other than guideline:
- according to BASF-internal standard
- GLP compliance:
- no
Test material
- Reference substance name:
- Hex-3-yne-2,5-diol
- EC Number:
- 221-209-5
- EC Name:
- Hex-3-yne-2,5-diol
- Cas Number:
- 3031-66-1
- Molecular formula:
- C6H10O2
- IUPAC Name:
- hex-3-yne-2,5-diol
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: Rößling
- Sex:
- not specified
Administration / exposure
- Route of administration:
- subcutaneous
- Vehicle:
- water
- Doses:
- 20, 50, 79, 126, 204, 316, 1260 mg/kg bw
- No. of animals per sex per dose:
- total: 26
- Control animals:
- no
- Details on study design:
- The test substance was given as 1 and 10% aqueous solution (pH 6)
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 100 mg/kg bw
- Based on:
- test mat.
Any other information on results incl. tables
cmm = µL = mg (density 0.996 g/ml)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
