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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Classification of Phenetole for effects in the environment

Several major guideline – estimation values (Klimisch 2) are available for Phenetole, indicates no toxic effect on fish and other trophic levels.  Thus, the value which have been considered for further calculation (invertebrate) is LC50 = 2.7 mg/L.


In determining the classification appropriate to Phenetole, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.



Reliable studies are available to demonstrate that Phenetole is non persistent in nature and so is considered to have rapid biodegradation in the environment. In other words Phenetole degradation may therefore be expected to be fast. Thus it can be inferred that Phenetole is non persistent in character. 


Phenetole is non persistent and so do not satisfy the criteria for classification as persistent (P). 


Potential to accumulate

Measured log Kow values for Phenetole is less than 4 (Log Kow = 2.041). The potential for Phenetole to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.  


 The calculated BCF of Phenetole is 21 dimensionless and below the threshold of 2000. 


Phenetole does not satisfy the criterion for classification as bioaccumulative (B).


The toxicity values of fish, invertebrates and algae are LC50 = 32.95 mg/L, LC50 = 2.7 mg/L are NOEC = 3.211 mg/L, respectively. The end point result values indicate that the substance will have any effect as the values are within the classifying range. However the data is insufficient for classifying the substance. Thus, considering the CLP Criteria for aquatic classification of the substance and weight of evidence approach , it is concluded that Phenetole does not exhibit toxicity to the aquatic environment and so will not quality as toxic in nature.

So, Phenetole does not satisfies the environmental effects criterion for classification as toxic (T).


Thus it can be inferred that Phenetole neither is P & B (including vPvB) substance, nor will qualify as T.