Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 700-136-7 | CAS number: -
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- other: expert statement
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Well documented expert statement from an internationally recognized contract research organization. The expert statement has been based on a series of physicochemical and toxicology studies performed according to technical guidelines and in compliance with GLP in internationally recognized contract research organizations.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Expert statement based on a series of physicochemical and toxicology studies. Technical guidelines followed in these experimental studies are cited in the respective endpoint study records.
- GLP compliance:
- no
- Remarks:
- Considered unnecessary fo expert statement
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Radiolabelling:
- no
Test animals
- Species:
- other: Detailed in endpoint study records of in-vivo studies referred to in the present expert statement
- Strain:
- other: Detailed in endpoint study records of in-vivo studies referred to in the present expert statement
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Detailed in the endpoint study records of in-vivo studies referred to in the present expert statement.
Administration / exposure
- Type of coverage:
- other: Detailed in endpoint study records of in-vivo studies referred to in the present expert statement, if appropriate.
- Vehicle:
- other: Detailed in endpoint study records of in-vivo studies referred to in the present expert statement, if appropriate
- Duration of exposure:
- Detailed in endpoint study records of in-vivo studies referred to in the present expert statement, if appropriate.
- Doses:
- Detailed in endpoint study records of in-vivo studies referred to in the present expert statement.
- No. of animals per group:
- Detailed in endpoint study records of in-vivo studies referred to in the present expert statement.
- Control animals:
- no
- Remarks:
- Detailed in endpoint study records referred to in the present expert statement, if applicable
- Details on study design:
- Detailed in endpoint study records referred to in the present expert statement, if applicable
Results and discussion
- Signs and symptoms of toxicity:
- not specified
- Remarks:
- Detailed in endpoint study records of in-vivo studies referred to in the present expert statement.
- Dermal irritation:
- not specified
- Remarks:
- Detailed in endpoint study records of in-vivo studies referred to in the present expert statement.
Percutaneous absorption
- Parameter:
- percentage
- Absorption:
- 10 %
- Remarks on result:
- other: Expert statement, based on MW > 500 and log Pow < -1
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
