Registration Dossier
Registration Dossier
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EC number: 700-571-2 | CAS number: -
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
(28-d) EC50 320 mg/kg dw soil micro-organisms (read-across, reliability 2)
(28-d) NOEC 100 mg/kg dw soil micro-organisms (read-across, reliability 2)
Key value for chemical safety assessment
- Short-term EC50 for soil microorganisms:
- 320 mg/kg soil dw
- Long-term EC10 or NOEC for soil microorganisms:
- 100 mg/kg soil dw
Additional information
A nitrogen transformation test is available for GTL Gasoil (C8 -C26) (Clarke, 2010). The test was conducted in accordance with OECD 216 and GLP.
Soil microorganisms were exposed to GTL Gasoil (C8 -C26) at concentrations of 100, 180, 320, 560 and 1000 mg/kg (dry weight) for 28 days at a temperature of 21°C, in the dark, with addition of Lucerne-green-grass meal as a respiratory substrate. The inhibitory effect of the test substance on nitrogen transformation was determined by measurement of nitrate concentrations in soil samples taken on Days 7, 14, 21 and 28, in comparison to control samples.
The effect of the test substance on nitrogen transformation gave an EC50 of 320 mg/kg dw and a NOEC of 180 mg/kg dw.
Conclusion
Soil microorganism toxicity data are available for a GTL-derived substance in the relevant carbon number range for Alkanes, C16 -C18 branched and linear. For GTL Gasoil (C8-C26), the EC50 (28-d) was determined to be 320 mg/kg dw soil, and the corresponding NOEC was 100 mg/kg dw soil. It is likely that the effects observed in the study with GTL Gasoil (C8 -C26) are attributable to the lower carbon number constituents but in the absence of individual constituent data for the terrestrial compartment to support this, the worst-case EC50 and NOEC are read across to the registration substance. It is not possible to derive a meaningful PNEC for the terrestrial compartment from these whole-substance data.
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