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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Tetrabutyl urea (TBU) proved to be not readily biodegradable in a study conducted according to OECD Guideline 301 F (<=1.3% biodegradation after 28 d). he functional control reached the pass level > 60% after 14 d. Degradation results of the toxicity control indicate that TBU was not inhibitory to the inoculum at the concentration tested (100 mg/l).

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The ready biodegradation of tetrabutyl urea (TBU) was investigated in a study conducted according to OECD Guideline 301F over a period of 28 days and using activated sludge as inoculum collected from a sewage treatment plant treating mainly municipal wastewater. The biodegradation rate was determined by measurement of oxygen consumption. Inoculum blank, abiotic control, procedural/functional control with the reference substance sodium benzoate, and toxicity control using 100 mg/L test item and 100 mg/L reference compound were performed. TBU proved to be not readily biodegradable under the test conditions employed (<=1.3% biodegradation after 28 d). The functional control reached the pass level > 60% after 14 d. In the toxicity control containing both test and reference item 32.2% biodegradation occurred within 14 d thus indicating that TBU was not inhibitory to the inoculum at the concentration tested.