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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information


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Administrative data

Description of key information

The available data were both in the form of reviews, however both concurred that TBTO does not appear to possess neurotoxic effects.

Key value for chemical safety assessment

Additional information

Neither of the available studies, Schweinfurth H (1986) and Schweinfurth H et al (1986) were sufficient for assessment as both were reviews of literature and studies performed by the same laboratory.

Justification for classification or non-classification

The substance is included in the group of substances "tributyltin compounds" which is itself included in Annex VI to Regulation (EC) No 1272/2008 with Index Number 050-008-00-3. The entry has been assigned the hazard classification of STOT RE 1 H372 (Causes damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)).

Available information indicates very little effect on behavioural effects or changes to the central nervous system and spinal cord specifically.