Registration Dossier
Registration Dossier
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EC number: 806-919-0 | CAS number: 1356964-77-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substance is readily biodegradable, meeting the 10-day window.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The ready biodegradability of the substance was determined in a GLP study performed according to OECD TG 301B [Griffith AW, 2014]. The mean cumulative net percent CO2 evolved (percent biodegradation) from the aqueous test medium fortified with the substance at 10 mg C/L was 63.93% on day 28. The toxicity control on day 13 was 69.96%, which indicates that the test substance was not toxic to the inoculum in the test medium according to OECD Guideline 301B.
The cumulative net percent CO2 evolved from the procedural control was 67.85% of theoretical by day 10, thus meeting the “pass” criteria of the test (reaching 60% or greater CO2 evolution by day 14). This rapid biodegradation of sodium benzoate confirmed the presence of an active microbial population and system integrity.
Based on the extent of CO2 evolution during this study, the substance can be classified as “readily biodegradable” by the criteria set forth in OECD Guideline 301B since 61.14% CO2 evolution was achieved within a 10 day window of reaching 10% biodegradation.
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