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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 Feb-15 Apr 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
yes
Remarks:
visual estimation instead of analytical determination
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
visual estimation instead of analytical determination
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Deviations:
yes
Remarks:
visual estimation instead of analytical determination
GLP compliance:
yes (incl. QA statement)
Remarks:
GLP Compliance Monitoring Program, Health Care Inspectorate, Ministry of Health, Welfare and Sport, Den Haag, The Netherlands
Type of method:
flask method
Water solubility:
> 1 000 g/L
Temp.:
20 °C
pH:
11.2

After the stirring period, the test sample was clear and no undissolved test substance was observed. It was concluded that the water solubility was > 1000 g/L.

Conclusions:
Interpretation of results: very soluble (> 10000 mg/L)

Description of key information

> 1000 g/L at 20 °C, pH 11.2 (EU A.6, OECD 105, OPPTS 830.7840; flask method)

Key value for chemical safety assessment

Water solubility:
1 000 g/L
at the temperature of:
20 °C

Additional information

Because of a very high solubility, the value was estimated visually, and not using any analytical method.