Registration Dossier
Registration Dossier
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EC number: 233-058-2 | CAS number: 10026-11-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The key study retained for short-term toxicity to freshwater invertebrate is the limit test performed on Daphnia magna with a first loading rate of 100 mg ZrOCl2/L. Therefore, the concentration of the zirconium tetrachloride is estimated to have no acute effect at > 190 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 190 mg/L
Additional information
Three studies have been validated (Klimish 2) for short-term toxicity to aquatic invertebrates based on read-across with Zr compounds. The selected key study is a limit test performed with zirconium dioxide (ZrO2). In this test, no acute effect on Daphnia magna at an initial loading rate of 100 mg ZrO2/L i.e 190 mgZrCl4/L. This study was selected as key study in comparison to the others since it is the only test that has been performed on the OECD recommended test organisms (daphnids), according to the OECD guideline with very small deviations.
The other available studies support the non toxic effect of zirconium to aquatic invertebrates. Thus, a semi-static toxicity study with ZrOCl2 performed on Tubifex tubifex displayed a EC50 96 hours of 255 mg ZrCl4/L.
Another study conducted with zirconium metal on Hyallela azteca displayed no effect after 7 days exposure with maximum concentration of 3.15 mgZr/L (i.e. LC50 >8.05 mgZrCl4/L).
In conclusion, no acute effect of Zirconium (subsequently, zirconium tetrachloride) has been observed in toxicity tests performed with invertebrates.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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