Registration Dossier
Registration Dossier
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EC number: 203-729-4 | CAS number: 110-02-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data form international report
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- SIDS INITIAL ASSESSMENT PROFILE
- Author:
- OECD
- Year:
- 2 011
- Bibliographic source:
- UNEP publications
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Thiophene
- EC Number:
- 203-729-4
- EC Name:
- Thiophene
- Cas Number:
- 110-02-1
- Molecular formula:
- C4H4S
- IUPAC Name:
- thiophene
Constituent 1
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Study design
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- other: ErC50
- Effect conc.:
- 113 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- not specified
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- other: EbC50
- Effect conc.:
- 106 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- not specified
- Basis for effect:
- other: area under growth curve
- Duration:
- 72 h
- Dose descriptor:
- other: NOErC
- Effect conc.:
- 12 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- not specified
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- other: NOEbC
- Effect conc.:
- 12 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- not specified
- Basis for effect:
- other: area under growth curve
Applicant's summary and conclusion
- Conclusions:
- The reported ErC50 and EbC50 72h for Pseudokirchnerella subcapitata are respectively 113 and 106 mg/l based on a OECD n°201 study.
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