Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study, but not performed according to GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1981

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dichlorobenzoxazole
EC Number:
222-818-9
EC Name:
2,6-dichlorobenzoxazole
Cas Number:
3621-82-7
Molecular formula:
C7H3Cl2NO
IUPAC Name:
2,6-dichloro-1,3-benzoxazole

Test animals

Species:
rat
Strain:
Wistar
Sex:
female

Administration / exposure

Type of coverage:
occlusive

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
ca. 1 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Conclusions:
In an acute toxicity study performed on female rats LD50 dermal of the test item was determined to be ca. 1000 mg/kg body weight.