N,N-bis(3-aminopropyl)methylamine

Acute Toxicity: other routes

Administrative data

Endpoint:

acute toxicity: other routes

Type of information:

experimental study

Adequacy of study:

other information

Study period:

1963

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: No GLP, no guideline followed, not enough data to complete a full IUCLID record.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1963

Report date:

1963

Materials and methods

Test guideline

Qualifier:

no guideline available

GLP compliance:

no

Limit test:

yes

Test material

Test material information

Constituent 1

Reference substance name:

N,N-bis(3-aminopropyl)methylamine

EC Number:

203-336-8

EC Name:

N,N-bis(3-aminopropyl)methylamine

Cas Number:

105-83-9

Molecular formula:

C7H19N3

IUPAC Name:

bis(3-aminopropyl)(methyl)amine

Details on test material:

- Name of the test substance: Bis-(3-aminopropyl-9methylamine, no further data.

Test animals

Species:

mouse

Strain:

not specified

Sex:

not specified

Administration / exposure

Route of administration:

intraperitoneal

Vehicle:

water

Doses:

The mice were applied with 21 5 solution of teh test substance

No. of animals per sex per dose:

No data

Control animals:

not specified

Results and discussion

Effect levels

Effect levels 1

Sex:

not specified

Dose descriptor:

LD50

Effect level:

90 other: mm³

Based on:

test mat.

Remarks on result:

other: Equivalent to 0.09 mL/kg bw, obtained in mice with pH 11 21 % test solution.

Effect levels 2

Sex:

not specified

Dose descriptor:

LD50

Effect level:

450 other: mm³

Remarks on result:

other: quivalent to 0.45 mL/kg bw, obtained in mice with pH 7 21 % test solution

Any other information on results incl. tables

Symptoms observed: agitation, staggering, shortness of breath, cramps

In autopsy: following application of teh basic test substance solution, corrosion of the peritoneaum was observed.