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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

With high probability acutely not harmful to fish.

Key value for chemical safety assessment

Additional information

A guideline study on the toxicity of the test substance to fish was conducted according to DIN 38412 with the test species Leuciscus idus. At test termination after 96 h a LC50 > 500 mg/L (nominal) was determined.

Additionally, the acute toxicity of 2-(methylamino)ethanol (CAS 109-83-1) to fish was examined in a guideline study according to the National procedure recommendation F.1.1., Federal Environmental Agency [Bayer AG, 1984]. Brachydanio rerio was used as test species and the exposure time was 96 hours, giving a LC50 > 100 mg/L. This result is confirmed through an acute fish experiment performed by ICI Brixham Laboratory (1986) using Salmo gairdneri with a LC50 (96 h) of 100 mg/L.

There are four reliable guideline studies available on the toxic effects of different sulphite compounds on fish. Tested compounds were potassium sulphite (CAS 10117-38-1), dipotassium disulphite (CAS 16731-55-8), disodium disulphite (CAS 7681-57-4) and sodium sulphite (CAS 7757-83-7). Fish species used for toxicity testing were Brachydanio rerio, Oncorhynchus mykiss and Leuciscus idus. The lowest effect value was obtained in a test on Oncorhynchus mykiss with disodium disulphite as test substance. The LC50 (relating to SO3, nominal concentration) was determined to be 149.8 mg/L.

It should be noted that in most tests the mortality was related to the sulphite-induced oxygen depletion of the test medium: concentration levels that previously resulted in 100% mortality showed no effect at all when the test media was aerated during the test period. For the test with the trout Oncorhynchus mykiss, however, observed mortality was related to very low pH-levels in the test medium upon addition of the test substance.

Thus, neither 2-(methylamino)ethanol nor sulphite is considered as harmful to fish.